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All-In with Chamath, Jason, Sacks & Friedberg · Money & Markets · October 2026
Shkreli had just said he and a collaborator have tried every quantum computer in the world and can't get any of them to multiply 300 by 200. Asked whether he's short the sector, this was his answer. He argues quantum mostly speeds up one algorithm, integer factoring.
Very few. So Google has a few prototypes. IBM has a little cloud. Chelsea and I have tried every single quantum computer in the world. We cannot multiply 300 by 200 on any of these.
And you're shorting them?
Yeah, I've been shorting them. Unfortunately, we lost millions of dollars shorting quantum computing companies, but I told my wife that we gained billions in insight.
Right. It's not easy to time the markets. Yes. Definitely. So
where is the natural computational edge? I mean, some people would say it's going to be towards encryption and defeating encryption because now we can actually use what it's actually good at to essentially brute force solutions to things that we can't solve today.
I think it's crazy to even think about it because we have a computational problem that we're trying to solve. And every time somebody uses the word AI, I actually think of the word MATMOL. These are Matmol machines. And I think that as we