RK Razib Khan's Unsupervised Learning

Podcast

Razib Khan's Unsupervised Learning

Razib Khan engages a diverse array of thinkers on all topics under the sun. Genetics, history, and politics. See: http://razib.substack.com/

Website ↗ Last published 30 October 2026 721 posts collected by Sputnik

Said on Razib Khan's Unsupervised Learning

“We'll get to 1 billion, and even really the full population of the Earth except a few people who abstain. The reason for this is the clinical utility of polygenic scores and genetic predictors… The cost-benefit calculus in medical genetics in clinical use will switch completely very soon. In fact, I would argue it's already switched.” — Jonathan Beauchamp, Razib Khan's Unsupervised Learning
Jonathan Beauchamp · 30 Oct 2026 Listen →
“France doesn't live above its means. The French government lives above it. That's a different thing. Essentially, what we're doing is that we're running massive public deficits largely to give benefits to old people. And then those old people actually save a lot of money, which is paradoxical.” — Philippe Lemoine, Razib Khan's Unsupervised Learning
Philippe Lemoine · 23 Oct 2026 Listen →
“I'm not worried about AI designing a virus that kills us all. Not really. It's a theoretical risk, whatever. I'm not worried about a paperclip maximizer. I am worried about if one company or one nation or one company regulated by one nation is the only one that has frontier AI. That worries me far, far more.” — Ramez Naam, Razib Khan's Unsupervised Learning
Ramez Naam · 22 Oct 2026 Listen →
“There is no world in which a software only loop has an exponent even close to one. It's well below that. And that says that these things are diminishing returns. … So, I don't doubt RSI. I doubt the consequences of RSI.” — Ramez Naam, Razib Khan's Unsupervised Learning
Ramez Naam · 22 Oct 2026 Listen →
“It's important to see your life as having a shape, that is having a plot, and having a plot and having a shape means you're going to die… the transhumanists, that want to live forever, either in their own bodies or in some kind of mechanical form, I think those people are deeply ultimately nihilistic and don't really have a sense of what life is for.” — Jerry Z. Muller, Razib Khan's Unsupervised Learning
Jerry Z. Muller · 19 Oct 2026 Listen →
“AI is one of those really transformative technologies that is creating tremendous new possibilities and realities and is deflating the value of the human capital that some people have accumulated. If you were a computer science major graduating in 2011, things look great for you, much less so if you're graduating in 2026 or 2028.” — Jerry Z. Muller, Razib Khan's Unsupervised Learning
Jerry Z. Muller · 19 Oct 2026 Listen →
“With the decades of political backlash against technology that we've seen already in the U.S., where in California, for example, you can't build an apartment building. You can't build a data center. You can't build a solar farm. You can't build an oil refinery. If you can't build any of these things, like what makes you think the government is going to allow you to build superintelligence? It's not going to happen.” — Theo Jaffee, Razib Khan's Unsupervised Learning
Theo Jaffee · 15 Oct 2026 Listen →
“…the purpose of a product is not to build a fucking website. If it is, then yeah, maybe I can do it and maybe Squarespace can do it. Maybe like a dude in Timbuktu could do it.” — Nikolai Yakovenko, Razib Khan's Unsupervised Learning
Nikolai Yakovenko · 10 Sep 2026 Listen →
“We have a lot of people in Silicon Valley for the last few years running around talking about basically AGI, AGI. It's like they want, it's like they're looking for AI Jesus or something to save the world or destroy the world.” — Collin Hogue-Spears, Razib Khan's Unsupervised Learning
Collin Hogue-Spears · 23 Aug 2026 Listen →

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Guests

Nikolai Yakovenko (10 episodes), Christopher Rufo (3 episodes), Dan Hess (3 episodes), Gregory Cochran (2 episodes), Mike White (2 episodes), Daniel Tabin (2 episodes), Collin Hogue-Spears (2 episodes), Brianna Wu (2 episodes), Aaron Renn (2 episodes), Leonidas-Romanos Davranoglou (2 episodes), Chris Masterjohn (2 episodes), Leighton Akira Woodhouse (2 episodes), and 27 more.