TW This Week in Startups

Podcast

This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world's greatest founders, operators, investors, and innovators.

Website ↗ Last published 3 November 2026 960 posts collected by Sputnik

Said on This Week in Startups

“We need to have the equivalent of like cyber Septembers. Not that you're trying to sell goods at a discount, but that everybody stops releasing new features for every September and just works on patching, updating. The entire industry says no releasing of new features. That's the month we're going to secure everything.” — Jason Calacanis, This Week in Startups
Jason Calacanis · 30 Oct 2026 Listen →
“I think the new moat is that you're relentless and that people trust you. And that would fall under brand. So we should have a new focus on brand today. … That kind of hospitality is a moat. Most people would say, oh, that's not a real moat. It's not a technical moat. How you make that customer feel, and how they feel you're being attentive towards them means everything.” — Jason Calacanis, This Week in Startups
Jason Calacanis · 30 Oct 2026 Listen →
“The thing I don't like about being anthropic right now is every person in the world has a huge financial incentive to figure out how to compete with your product cheaper. Okay. Everybody, like, it's the biggest, biggest pot of gold in human history is to figure out how to offer intelligence for free right now. So, you know, I don't like the idea of having that target on my back.” — D.A. Wallach, This Week in Startups
D.A. Wallach · 29 Oct 2026 Listen →
“The actual greatest business in the history of the stock market over the past hundred years… was Altria, Philip Morris. And you go, well, why was that such a great business? Well, enormous gross margins and an incredibly addictive product with virtually unlimited demand… So I think the fundamental question for Anthropic and all the players in this market is basically, is intelligence the new cigarettes, right?” — D.A. Wallach, This Week in Startups
D.A. Wallach · 29 Oct 2026 Listen →
“If you look at any company or any team, something like 10% of what you do is written down and 90% is spoken. It's all forgotten. And so where does that all go? And how do I make that actionable for you?” — Shishir Mehrotra, This Week in Startups
Shishir Mehrotra · 17 Oct 2026 Listen →
“Consider this, that there are about 5,000 people in the world that have frontier access to frontier models within the closed labs. And of those, probably 10% do safety research. So in the whole world, our whole world is being secured today by 500 people. No matter their intention, it is impossible that they'll secure these brains.” — Misha Laskin, This Week in Startups
Misha Laskin · 14 Oct 2026 Listen →
“It basically works the opposite of a cell phone, right? The more cell phones you get in an area, the worse they all work. The more totems you get in an area, the better they all work.” — Carter Fowler, This Week in Startups
Carter Fowler · 12 Oct 2026 Listen →
“Every generation of technology seems to exacerbate the skew of outcomes of every young generation. One way to say it is it seems like the median gets slightly worse, but the extremes get immensely powerful.” — Deedy Das, This Week in Startups
Deedy Das · 8 Oct 2026 Listen →
“…the LLMs and these AI companies are cannibalizing the data that they rely on for training. Like you see, think about how many bloggers, wirecutters, these types of posts that used to exist in the world are disappearing because there's no incentive to write them anymore. They're just going to get sucked up immediately.” — Zach Hudson, This Week in Startups
Zach Hudson · 19 Aug 2026 Listen →

Hosts

This Week in Startups is hosted by Alex Wilhelm , Molly Wood , Lon Harris , Sunny Madra and David Weisburd .

Recent Episodes

  1. 3 Nov 2026

    Odyssey CEO Oliver Cameron is 90% sure we live in a simulation | E2358

    With Oliver Cameron

  2. 30 Oct 2026

    Binance Hacked $6.3B Stolen, DoorDash Buys Instacart For $17B, Jake Newfield from Hermetiq, + More!

    With Jake Newfield

  3. 29 Oct 2026

    Is AI the new cigarettes? Our VC panel digs into Anthropic’s S-1 | E2356

    With D.A. Wallach , Dave McClure and Ben Black

  4. 26 Oct 2026

    Pregame Your Launch Before Your App Exists (w/ Amanda Bradford) | E2355

    With Amanda Bradford

  5. 24 Oct 2026

    OpenAI’s $1.25T Raise, Starlink Mobile & Zuck’s Tax Deal | EP 2354

    With Keith Piras

  6. 22 Oct 2026

    We asked 3 VCs: would you invest in Elizabeth Holmes’ next startup? | E2353

    With Sam Lessin , Paige Finn Doherty and Jenny Fielding

  7. 20 Oct 2026

    Anthropic Gives Away 5% of Its Shares, Clone’s Muscle Robot, ElevenLabs Steals Podcaster's Voice

    With Dhanush Radhakrishnan

  8. 17 Oct 2026

    Flying Cars, OpenAI Spies, Why AI Isn’t Sticking (Superhuman CEO)

    With Shishir Mehrotra

  9. 14 Oct 2026

    The Ex-DeepMind Researcher Taking On China’s Open Source AI

    With Misha Laskin

  10. 12 Oct 2026

    The Gadget That's Better in Crowds Than Your Phone + Ring’s Founder Before Amazon Bought It | E2349

    With Carter Fowler

  11. 10 Oct 2026

    Jason Reacts To Japanese Founder Pitches + Fireside Chat With Yuki Shirato

    With Yuki Shirato and Keith Piris

  12. 8 Oct 2026

    What VCs Really Think About Personal AI Agents | E2347

    With Deedy Das , Kanu Gulati , Chris Farmer and Sheel Mohnot

Guests

Vinny Lingham (22 episodes), Scott Orn (12 episodes), Becki DeGraw (12 episodes), Dave McClure (6 episodes), Deedy Das (5 episodes), Brad Gerstner (5 episodes), Kelly Schricker (5 episodes), Mark Suster (5 episodes), Zach Coelius (4 episodes), Paige Doherty (4 episodes), Shishir Mehrotra (4 episodes), Delian Asparouhov (4 episodes), and 757 more.