Podcast

Invest Like the Best (Patrick O'Shaughnessy)

Conversations with the best investors and business leaders in the world. We explore their ideas, methods, and stories to help you better invest your time and money. Hear stock market and boardroom insights you can't find anywhere else. If you're a professional investor, CEO, entrepreneur, or business strategist, this is for you. Explore all our episodes and learn more at https://www.colossus.com

Website ↗ Last published 27 October 2026 603 posts collected by Sputnik

Hosts

Invest Like the Best (Patrick O'Shaughnessy) is hosted by Patrick O'Shaughnessy and Zack Fuss .

Said on Invest Like the Best (Patrick O'Shaughnessy)

“Look, you're really smart. So you must understand. Being smart has limits. … If that experiment requires breeding mice and mice need a year to grow up and die, that experiment is going to take time. And it might be a great experiment. You might learn a lot and that's great. Still going to take time. And the lab's only so big.” — Cliff Sosin, Invest Like the Best (Patrick O'Shaughnessy)

Cliff Sosin · 2026-10-27 Permalink → Listen →

“I found it helpful to assume everyone has really great intelligence and ask what's left. The pushback is often some version of, but you don't understand how hard this is, and you don't understand how complicated this is. … And my hand-wavy and approximately right response is, okay, sure, but that's all just intelligence. And to follow this logic all the way through to the end is if intelligence becomes cheap and ubiquitous, what you want to own are the complements to intelligence.” — Cliff Sosin, Invest Like the Best (Patrick O'Shaughnessy)

Cliff Sosin · 2026-10-27 Permalink → Listen →

Christina Cacioppo · 2026-10-20 Permalink → Listen →

“Go talk to the inference providers. They will say, look, the reason to post-train a model is cost. Some businesses have that need, but there is not a quality reason to do it. There's kind of a marketing reason to do it right now in this environment. And I think there's a lot of post-training for marketing reasons, for investors and for customers, mostly for investors, actually.” — Christina Cacioppo, Invest Like the Best (Patrick O'Shaughnessy)

Christina Cacioppo · 2026-10-20 Permalink → Listen →

“People are real smart. So if you try to charge them based on tokens, they are very quick to say, oh, you've just marked up a Claude token 4x. Are you 4x as good as Claude? I don't know. Let me go try it out. You actually put yourselves in a competitive position against the models that probably no application really wants to be in. … If you're trying to mark up at all, users are very smart and you will lose on that comparison.” — Christina Cacioppo, Invest Like the Best (Patrick O'Shaughnessy)

Christina Cacioppo · 2026-10-20 Permalink → Listen →

“Today, there's about 190 currencies around the world. My view is that 10, 20 years from now, those 190 will be maybe 10, because the fiscal situation in so many countries around the world is so dire that a lot of that fiat money is not real money.” — David Vélez, Invest Like the Best (Patrick O'Shaughnessy)

David Vélez · 2026-10-13 Permalink → Listen →

“There's about $15 trillion of retail deposits in the US banking system, but banks pay on average about 40 basis points on yield a year. … That's more or less $600 billion that are going to banks to pay for banking branches that in a digital banking environment would actually stay in consumers' pockets. So this is a massive wealth tax, the fact that banks don't pay any yield.” — David Vélez, Invest Like the Best (Patrick O'Shaughnessy)

David Vélez · 2026-10-13 Permalink → Listen →

“OpenAI is kind of like mainline. They go to church every Sunday. They're sort of like evangelicals. That's Anthropic.” — Ben Thompson, Invest Like the Best (Patrick O'Shaughnessy)

Ben Thompson · 2026-08-18 Permalink → Listen →

“There's two things to understand about consumers that Silicon Valley has to relearn about every 10 years. Number one, consumers do not want to pay for software. And number two, consumers do not care about being productive.” — Ben Thompson, Invest Like the Best (Patrick O'Shaughnessy)

Ben Thompson · 2026-08-18 Permalink → Listen →

Recent Episodes

27 Oct 2026

Cliff Sosin - Owning the Complements to Intelligence - [Invest Like the Best, EP.497]

With Cliff Sosin
20 Oct 2026

Christina Cacioppo - Building an Enduring Software Company in the Age of AI - [Invest Like the Best, EP.496]

With Christina Cacioppo
13 Oct 2026

David Vélez - Building Nubank and the Future of Global Banking - [Invest Like the Best, EP.495]

With David Vélez
6 Oct 2026

Andrew Huberman - The Frontier of Neurotechnology - [Invest Like the Best, EP.494]

With Andrew Huberman
28 Sep 2026

Noah Shinn - Building Instinct: The Personal Agent - [Invest Like the Best, EP.493]

With Noah Shinn
22 Sep 2026

Gabe Stengel - Building Investing Superintelligence - [Invest Like the Best, EP.492]

With Gabe Stengel
16 Sep 2026

Michael Moritz - Lessons From 40 Years of Investing and Writing - [Invest Like the Best, EP.491]

With Michael Moritz
8 Sep 2026

Walter Russell Mead - How America Keeps Winning - [Invest Like the Best, EP.490]

With Walter Russell Mead
1 Sep 2026

Sarah Guo - Funding the Frontier - [Invest Like the Best, EP.489]

With Sarah Guo
25 Aug 2026

Neil Movva - Making AI 10x Cheaper - [Invest Like the Best, EP.488]

With Neil Movva
18 Aug 2026

Ben Thompson on Big Tech, China, and the AI Boom Running Out of Money - [Invest Like the Best, EP.487]

With Ben Thompson
11 Aug 2026

Eric Vishria - A Decade of Lessons Investing in Software & Hardware - [Invest Like the Best, EP.486]

With Eric Vishria

Guests

Boyd Varty (7 episodes), Gavin Baker (7 episodes), Brent Beshore (7 episodes), Bill Gurley (6 episodes), Michael Mauboussin (6 episodes), David Senra (5 episodes), Jeremiah Lowin (5 episodes), Ted Seides (5 episodes), Sam Hinkie (5 episodes), Ali Hamed (4 episodes), Peter Attia (4 episodes), John Collison (4 episodes), and 503 more.

Sputnik Intelligence Half price

Follow everything said on Invest Like the Best (Patrick O'Shaughnessy), with your own AI agent.

Sputnik collects podcasts and newsletters every day. Connect Claude, ChatGPT or Codex and ask it about anyone in them.

Full transcripts, with speaker names
Updated daily
Newsletters too, including email-only ones
Alerts when they get mentioned
Every answer links to the source

Free trial, then ~~$100~~ $49 /month

14 days free. Cancel anytime.

Start free trial

Audience

Apple Podcasts genres: Investing, Podcasts, Business, Technology

Topics

ai compute infrastructure venture capital company culture ai business models enterprise software data center infrastructure capital allocation vertical integration frontier model economics semiconductor supply chain

In These Collections

Money & Markets Startups & Venture